Sunday 2 October 2011

DePuy ASR Hip Implants - long-term biological effects of exposure to orthopaedic metal alloys

Article by
Kevin Timms
At present there are many people who have concerns over their DePuy ASR hip resurfacing systems. The reason for this is that it has been reported that the DePuyASR hip replacement and hip resurfacing system have an abnormally high failure rate. In terms of statistics, this equates to 1 in 8 patients requiring revision surgery within 5 years of implantation.

The Nuffield Orthopaedic Centre in Oxford have published a study on the long-term biological effects of exposure to orthopaedic metal alloys. The study particularly focused on Cobalt and Chromium ions derived from metal on metal wear debris from medical implants such as hip implants.

A pseudotumour is defined as a tumour like mass resulting from inflammation, fluid accumulation or other causes. The study has suggested that such pseudotumours may present with a major nerve palsy (which is a collective term for a range of nervous disorders that result in weakness or immobility of nerves in some region of the body).

The study advises that “preoperative neurohysiological studies showed severe and irreversible pathological changes to nerve function with neurohistopathological evidence of complete nerve destruction with a previously unreported pathological appearance”. This may represent what may be a toxic pathological process resulting from metal on metal wear debris.

This study is not directly aimed at the DePuy ASR hip implants but metal on metal hip implants as a whole. However, it does confirm that there are severe injuries which patient’s could suffer if they do not regularly seek medical advice.

If you have had a DePuy ASR hip replacement or hip resurfacing system and are experiencing adverse symptoms such as pain, swelling or having problems walking please contact Kevin Timms within the product liability team at Garden House Solicitors to discuss whether you are entitled to claim compensation for injuries sustained as a result of a failed DePuy ASR hip implant or other metal on metal hip implant.

Kevin can be contacted on             01992 422 128 begin_of_the_skype_highlighting            01992 422 128      end_of_the_skype_highlighting       or email him at


  1. The effect of defective medical device such as hip recall is for a long term period and may cause serious medical injuries and complications.

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